Principal Laboratory Research Scientist – Li Lab Full Time

The Crick

Principal Laboratory Research Scientist – Li Lab page is loaded Principal Laboratory Research Scientist – Li Lab Apply locations London time type Full time posted on Posted 2 Days Ago job requisition id R1552

Salary for this Role:

From £49,950, subject to skills and experience

Job Title:

Principal Laboratory Research Scientist – Li Lab

Reports to:

Leanne Li

Closing Date:

31/Mar/.59 GMT

Job Description:

Principal Laboratory Research Scientist

Reporting to: Leanne Li

Contract term: This is a permanent position on Crick terms and conditions of employment.

Provides senior level support to a Group Leader either in a lab management role or as a technical expert. May have an established scientific reputation.

The Role

The role of a Principal Laboratory Research Scientist in the Crick is diverse and rewarding. The role covers a wide range of different functions and allows for continuity of lab operations. The role offers support to one or more scientific projects or programmes. Typical activities include:

• Collaborating with other lab members on research projects.

• Providing experimental or technical support to other lab members.

• Providing technical expertise and input for the development, optimisation and troubleshooting of relevant and novel methodologies.

• Independently undertaking own research projects, designing, and executing experiments in consultation with the group leader.

• Initiating and managing long-term investigations and collaborations with other researchers.

• Participating in academic activities, including group meetings and journal clubs, seminars, and scientific meetings.

• Writing up findings for publication and completing revisions.

• Organisation and management of the laboratory, including maintaining laboratory databases, ordering of laboratory supplies, monitoring budgets, and routine maintenance of laboratory equipment.

• Training and supervising other lab members in key techniques and protocols, lab operations, and equipment use.

• Liaising with Science Operations and attending key quadrant meetings.

• Writing risk assessments and SOPs and providing safety guidance to lab members.

The Research Group

The Li Lab performs cutting edge research in the emerging field of Cancer Neuroscience. We systematically dissect the crosstalk between cancer, the nervous system and the immune system, using a panel of genetically engineered mouse models of cancer combined with contemporary neuroscience methodologies.

Key responsibilities

These include but are not limited to:

• Maintaining laboratory organisation and supplies

• Managing colonies of various complicated genetically engineered mouse models

• Supporting the Group Leader in day-to-day operations

• Deputising for the Group Leader when unavailable

• Training new and existing lab members in standard operating procedures and, where necessary and agreed by the Group Leader, members of other labs

• Training new lab members in Containment Level 3 practices

• Developing, writing, and maintaining Risk Assessments

• Establishing new methodologies in the lab

• Developing proof-of-concept for new research directions

• Facilitating collaborations within and outside the Crick

• Independently devising and leading research projects

• Presenting data and findings to internal and external audiences

• Writing up research projects for publication

Experience and Competencies

The post holder should embody and demonstrate our core Crick values:

Bold; Open; Collegial

Essential

• PhD in neuroscience or immunology, or related fields

• Substantial post-PhD experience in neuroscience or immunology research

• Significant experience working with genetically engineered mouse models

• Experience in managing colonies with complicated transgenic backgrounds

• Strong research track-record evidenced by peer-reviewed publications

• Strong communication skills to audiences of varied expertise

• Ability to prioritise and manage own time

• Ability to work collaboratively

• Experience in lab management

• Extensive experience in writing and maintaining Risk Assessments for Containment Level 2 and 3

• Eagerness and ability to devise and lead independent research projects on how the nervous system interacts with the immune system, and how such crosstalk impacts cancer progression

• Experience in training others in new techniques to a high standard

• Ability to develop and optimise new scientific research methods

• Ability to contribute to research strategy based on current scientific literature

Desirable

• UK Home Office Personal Licence (including surgery module)

• Expertise in cell culture, electrophysiology, in vivo imaging, advanced imaging, FACS, preclinical trials, mouse surgeries, etc.

About Us

At the Crick, we conduct research at the forefront of biomedical research. We combine rigour with an open and collaborative culture, and are outward-looking, reflecting our status as a partnership of six organisations aiming to pool knowledge, ideas and resources.

We have a wide research portfolio with no divisions or departments, bringing biomedical researchers together with clinicians, physical scientists and applied scientists from our pharmaceutical partners.

We aim to attract the most talented researchers and support them to tackle innovative research questions. Our science technology platforms provide our researchers with access to state-of-the-art technology and expertise.

We provide an excellent learning environment with dedicated education programmes in public engagement with science, education and personal development, and a postdoc training programme that prepares scientists for leadership roles in science.

• If you are interested in applying for this role, please apply via our website.

• All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

• If you require a visa to work in the UK we will help support your application should you be successful

Find out what benefits the Crick has to offer:

For more information on our great pay and benefits package please click here:

Equality, Diversity & Inclusion:

We welcome applications from all backgrounds. We are committed to providing equal employment opportunities, regardless of ethnicity, nationality, gender, sexual orientation, gender identity, religion, pregnancy, age, disability, or civil partnership, marital or family status. We particularly welcome applications from people who are Minority Ethnic as they are currently underrepresented in the Crick at this level.

Diversity is essential to excellence in scientific endeavour. It increases breadth and perspective, leading to more innovation and creativity. We want the Crick to be a place where everyone feels valued and where diversity is celebrated and seen as part of the foundation for our Institute’s success.

The Crick is committed to creating equality of opportunity and promoting diversity and inclusivity. We all share in the responsibility to actively promote dignity, respect, inclusivity and equal treatment and it is our aim to ensure that these principles are reflected and implemented in all strategies, policies and practices.

Read more on our website:

The Francis Crick Institute is a biomedical discovery institute researching the biology underlying human health.

At the Crick, scientists and staff collaborate to stretch the very limits of what we know about how life works. Our work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections and neurodegenerative diseases.

The Francis Crick Institute is a charity, founded by the Medical Research Council, Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.