Principle Scientist – Translational Research Full Time

Barrington James Limited
Overview

(Neurodegeneration/Renal Disease)

Barrington James is partnering with a leading biopharmaceutical organization to find a skilled Principal Scientist for their Translational Unit. This lab-based role will focus on Neurodegeneration or Renal Disease, bridging the gap between preclinical research and early clinical studies through translational assays in human-derived cells, tissues, and biofluids.

Responsibilities

• Design and execute laboratory experiments to drive scientific understanding and support drug discovery in neurodegeneration or renal disease.
• Lead the identification, validation, and development of clinical biomarkers and deployable biomarker assays.
• Apply advanced laboratory techniques including ELISA, flow cytometry, gene/protein expression analysis and proteomics.
• Troubleshoot assays and collaborate with cross-functional teams to ensure robust study designs.
• Ensure accurate, detailed lab records and compliance with data integrity and safety protocols.

Requirements

• Essential:
• PhD in a relevant scientific discipline (e.g., Molecular Biology, Genetics, Immunology, etc.).
• 3-5+ years of experience in translational research and biomarker development.
• Expertise in handling primary human cells and performing laboratory techniques such as ELISA, flow cytometry, and gene expression analysis.
• Experience in either neurodegenerative diseases or renal diseases.

• Preferred:
• Strong problem-solving abilities and capability to critically analyse scientific data.
• Excellent communication skills, both written and verbal, with the ability to present complex data clearly to internal and external stakeholders.
• Ability to manage multiple priorities, meeting deadlines while maintaining high-performance standards.
• Independent and collaborative, with a proven track record of defining strategic approaches to research goals.

This is a fantastic opportunity to join a dynamic and innovative team and make an impact in drug discovery. Apply now to take your career to the next level.

Open to candidates eligible to work in the UK. Recruitment handled by Barrington James.